WHY A NEW TECHNOLOGICAL PLATFORM FOR STENTS
THERE IS AN UNMET CLINICAL NEED FOR SITE-SPECIFIC,
EASILY REMOVABLE, LARGE CALIBER STENTS
FOR USE IN BENIGN AS WELL AS IN MALIGNANT OBSTRUCTIONS
Stenting constitutes an indispensable and increasingly popular tool in the minimally-invasive management of a wide variety of circulatory disorders. They are scaffolding devices intended to restore and sustain the natural circulatory pathways to allow flow of blood, bile, urine etc. Apart from the vascular ones, the use of stents has been held up by the lack of stents that are configured for the shapes, precise conditions and peculiarities of the obstructed pathway.
A fundamental of stent design should be that every stent must be adapted to the individual characteristics of the organ to be implanted.
There are many companies producing stents today. Each has a basic stent design that is then adapted to different applications. Mostly the changes are to the stents' caliber, length, wire thickness etc. without making any significant changes to fundamentally adapt the stent to the function of the organ. In fact, most of the current non-vascular stents are derived from designs used by vascular stents. This is particularly relevant if the disease site to be treated has a peristaltic movement or it is near to a sphincter. If a stent's caliber is larger than the adjacent sphincteric caliber, then a disturbance is caused to the closure of the sphincter or to the advance of the peristaltic wave. For example, incontinence may occur if the stent is near the urethral sphincter. In addition a reactive tissue proliferation can develop at the ends of the stent.
Allium has developed a proprietary stent technology platform to expedite the development of site-specific stents. Each Allium stent is designed specifically to match the site to be treated and the surrounding anatomy. This proprietary technological platform allows Allium to produce thin walled, entirely covered stents with a large lumen, comparable to the uncovered or partly covered permanent stents but with the critical advantage of removability.
- Unique Coating - fully covered by a polymeric coating designed to prevent tissue in-growth into the lumen as well as reduce encrustation, stone formation and calcification.
- High Flexibility - extremely flexible to ensure minimal tissue irritation, to adapt to the shape and curves of the organ for excellent comfort.
- Full Clinical Adaptability – site specific design to allow optima fit to the anatomy and function of the target organ
- Non-shortening Structure - allowing accurate placement during deployment
- Varying radial forces along the stent body – High radial force main body and low radial force ends act to reduce the possibility of Stent migration, Vesico-ureteral reflux, Development of reactive proliferative tissue (candy- wrap effect) at its ends.
- Strong stability - safe and effective anchoring for preventing migration
- Easy Placement - radiopaque markers on the stent allow for insertion under vision and/or fluoroscopy for accurate positioning while permitting simple removal at any stage.
- Long Term Indwelling - intended for a long indwelling period and can eliminate the need for recurrent procedures.
- Reduced Migration - designed with an intravesical anchor to decrease upward migration into the ureter.
- Easy and Safe Removal - stent is retrieved by unraveling it into a thread-like strip.